Earnings schedule for week of 4/2/2012

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Tales from the crypt lead researchers to cancer discovery

Public release date: 30-Mar-2012
[ | E-mail | Share ]

Contact: Chris Gunter or Holly Ralston
cgunter@hudsonalpha.org
256-327-0400
HudsonAlpha Institute for Biotechnology

HUNTSVILLE, Ala Tales from the crypt are supposed to be scary, but new research from Vanderbilt University, the HudsonAlpha Institute for Biotechnology and colleagues shows that crypts can be places of renewal too: intestinal crypts, that is. Intestinal crypts are small areas of the intestine where new cells are formed to continuously renew the digestive tract. By focusing on one protein expressed in our intestines called Lrig1, the researchers have identified a special population of intestinal stem cells that respond to damage and help to prevent cancer.

The research, published in the March 30 issue of Cell, also shows the diversity of stem cells in the intestines is greater than previously thought.

"Identification of these cells and the role they likely play in response to injury or damage will help advance discoveries in cancer," said Shawn Levy, Ph.D., faculty investigator at the HudsonAlpha Institute and an author on the study.

The intestines and colon are normally lined with a single layer of cells to absorb nutrients from food. There are regular small pockets in the intestines called crypts, where stem cells are gathered. Rapid turnover of the lining cells and replacement by new lining cells made in the crypt, keep the intestines and colon healthy and keep damaged cells from turning into cancerous ones.

The new paper demonstrates that, although the makeup of stem cells in the crypt is still controversial, one protein called Lrig1 can distinguish a group of long-lived cells at the base of the crypt. These Lrig1-positive stem cells do not regularly replace lining cells, but instead are only activated when there is damage or injury to the intestine.

In addition, the researchers show that the Lrig1 protein functions to prevent cancer as a tumor suppressor molecule. When the protein is completely absent from a mouse model, the mice all develop adenomas and then tumors. This suggests that Lrig1 is an important target for understanding and treating intestinal and colon cancer.

Levy added, "RNA sequencing work at HudsonAlpha found that the Lrig1-positive stem cells are molecularly different in multiple ways from previously identified crypt stem cells, in keeping with their role in responding to damage." Further work on genes expressed or silenced in this population of cells, he added, will increase understanding of both normal and cancer cell progression in the intestines.

###

The paper can be found at Cell.com.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 30-Mar-2012
[ | E-mail | Share ]

Contact: Chris Gunter or Holly Ralston
cgunter@hudsonalpha.org
256-327-0400
HudsonAlpha Institute for Biotechnology

HUNTSVILLE, Ala Tales from the crypt are supposed to be scary, but new research from Vanderbilt University, the HudsonAlpha Institute for Biotechnology and colleagues shows that crypts can be places of renewal too: intestinal crypts, that is. Intestinal crypts are small areas of the intestine where new cells are formed to continuously renew the digestive tract. By focusing on one protein expressed in our intestines called Lrig1, the researchers have identified a special population of intestinal stem cells that respond to damage and help to prevent cancer.

The research, published in the March 30 issue of Cell, also shows the diversity of stem cells in the intestines is greater than previously thought.

"Identification of these cells and the role they likely play in response to injury or damage will help advance discoveries in cancer," said Shawn Levy, Ph.D., faculty investigator at the HudsonAlpha Institute and an author on the study.

The intestines and colon are normally lined with a single layer of cells to absorb nutrients from food. There are regular small pockets in the intestines called crypts, where stem cells are gathered. Rapid turnover of the lining cells and replacement by new lining cells made in the crypt, keep the intestines and colon healthy and keep damaged cells from turning into cancerous ones.

The new paper demonstrates that, although the makeup of stem cells in the crypt is still controversial, one protein called Lrig1 can distinguish a group of long-lived cells at the base of the crypt. These Lrig1-positive stem cells do not regularly replace lining cells, but instead are only activated when there is damage or injury to the intestine.

In addition, the researchers show that the Lrig1 protein functions to prevent cancer as a tumor suppressor molecule. When the protein is completely absent from a mouse model, the mice all develop adenomas and then tumors. This suggests that Lrig1 is an important target for understanding and treating intestinal and colon cancer.

Levy added, "RNA sequencing work at HudsonAlpha found that the Lrig1-positive stem cells are molecularly different in multiple ways from previously identified crypt stem cells, in keeping with their role in responding to damage." Further work on genes expressed or silenced in this population of cells, he added, will increase understanding of both normal and cancer cell progression in the intestines.

###

The paper can be found at Cell.com.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

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Poop-to-power tech begins to smell reasonable

15 hrs.

John Roach

Researchers have created a microbial fuel cell that can convert about 13 percent of the energy in raw sewage into electricity as it helps clean up municipal wastewater.

The technology under development is an improvement from two percent efficiency just a year ago, researchers at the J. Craig Venter Institute?reported Wednesday at the annual meeting of the American Chemical Society.

?That actually puts us in a realm where we could produce a meaningful amount of electricity if this technology is implemented commercially,? Orianna Bretschger, who presented the development, said in a news release.

The idea is to use the electricity generated from the microbial fuel cell to clean up wastewater for no additional energy costs. Some estimates put the energy use of wastewater treatments plants at two percent of overall consumption in the U.S.

The team?s microbial fuel cell relies on naturally-occurring microbes in sewage that produce electrons and protons as they digest organic waste. While this isn?t the first or only microbial fuel cell under development, ?its efficiency is, as Bretschger said, ?a giant step in the right direction.?

What?s more, the fuel cell cleans up about 97 percent of the organic matter in wastewater. That?s not clean enough to drink ? need 99.9 percent for that ? but the fuel cell does a lot of the work, meaning less electricity is required for the other steps.

--Via Yale Environment 360

John Roach is a contributing writer for msnbc.com. To learn more about him, check out his website?and follow him on Twitter. For more of our Future of Technology?series, watch the featured video below.

Source: http://www.futureoftech.msnbc.msn.com/technology/futureoftech/poop-power-tech-begins-smell-reasonable-596938

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New Government ePayment Regulation Costs Small Business $10 Billion

The small business economy is suffering considerable harm from new regulations being enforced by the IRS this year. There?s a new tax form that?s causing this trouble for small business owners who collect ePayments and conduct eCommerce. The IRS Form 1099-K requires merchant processors and third-party payment processors, such as PayPal and Square, to report the income that individuals and small businesses were paid through their services to the IRS in 2011. ?The IRS estimates that 53 million of these forms should have been sent for tax year 2011, making it the 10th highest volume tax form in it?s first year of existence. That?s a lot of small businesses being hit by the implementation of Internal Revenue Code Section 6050W.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/tR5NbxTN1R0/

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SEO UK along with Social Media Marketing | Nichehosters: Hosting ...

Internet marketing would be the technique you can use in order to take your web business to new heights. This can be a greatest procedure to conquer your competitors and phone your own industry. The web offers the really extensive reach such as people all of avenues of life where ever they are around the world. The vastness, versatility, as well as quantity of the web help to make it a suitable channel for advertising your web business, regardless of what type as well as size.

Online marketing can be called Internet marketing because it essentially makes up SEO UK making use of search engine optimization as well as Ppc, as well as social internet marketing. You have to adopt the very best method in order to be an online success for your business, in addition to getting it in the cost-effective method. Nevertheless, you should make this happen with all the right stability along with the social media tools if you are using SEO UK to advertise your company. This is vital that you acquire a excellent exposure for that website as well as for your company on the internet.

SEO UK uses major tools to optimist the web site of the online business. Including internet analytic tools, Html code validating tools, keyword evaluation as well as research or UK SEO, as well as website popularity. Advertising specialists make use of the most dependable methods to be able to maximize potential customers and sales, such as search engine optimization as well as pay per click advertising.

Some great benefits of SEO UK are numerous, it doesn?t matter what your company goals are. SEO UK actively seeks qualified website visitors to find your website, as well as establishes the celebration prepared to obtain details about their search. It is a long procedure aside from the results, not really long-lasting. The optimizers of search engines include a great deal of efforts to keep the final results to have an extended time frame.

On the other hand, social internet marketing is becoming prominent by such social media systems as Twitter and Facebook. Apart from Twitter and Facebook, other popularly used websites in addition have numerous registered users in the role of a massive marketplace. They could turn out to be potential customers in the event that business online proprietors understand how to utilize this scenario. Internet businesses can certainly sell themselves to potential customers whilst getting along with them as well as interesting those to buy numerous as well as services. You may be resourceful and artistic in letting them join your own site?s competitions as well as fun activities to be emotionally installed on your service as well as services, hence driving them to compelled to purchase them. This kind of advertising could also be used as word-of-mouth advertising which can be now getting well-liked.

The death of those 2 methods though is based on having less dedication hence Online marketers should heighten their efforts as well as up-to-date on the efforts. That is required purchase to discover the real benefits of these kinds of advertising. Business owners should remain committed as well as dedicated to these to help make them benefit the nice or achievement from the business.

This entry was posted in SEO and tagged seo uk, UK SEO. Bookmark the permalink.

Source: http://blog.nichehosters.com/seo/seo-uk-along-with-social-media-marketing/

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Global Money Business Presentation Part 3 | The First Place To Find ...

Please visit www.globalmoneyunlimited.org for more info. Like us on Facebook at http to get latest updates. ** P5,000, P10,000, P50,000, Car LOANS at totally 0% interest! ? No collateral, no co-maker, no processing fee, no hassle ** Plus LIFE INSURANCE Benefit Package ? Protect your family from unexpected cost of medical expenses and accidents. ** Plus INCOME from Bonuses and Profit Sharing! ? Earn unlimited P500 and lots of cash from commissions, bonuses and company profit-sharing. What are you waiting for? Check us out today! www.globalmoneyunlimited.org http

Source: http://www.kai-st.com/?p=640

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Android 4.0.4 rears its head again, this time over at AOSP

It hasn't made its official open-source debut yet, but Android 4.0.4 should be hitting the repositories very soon. Leaks of the next Ice Cream sandwich update have been circulating since early February, and Moto's Xoom was given the first taste today. Now Jean-Baptiste Queru, an engineer on the mobile OS, has posted over at the Android Open Source Project forums to let us know that the appropriate files are being pushed as we speak. Of course, this doesn't mean that 4.0.4 will hit your handset any time soon... or ever, for that matter. But, it does mean that more custom ROM devs will be incorporating its pile of bug fixes into their products. Watch the source links to be alerted the moment it goes live.

Android 4.0.4 rears its head again, this time over at AOSP originally appeared on Engadget on Wed, 28 Mar 2012 15:41:00 EDT. Please see our terms for use of feeds.

Permalink Android Central  |  AOSP 1, 2  | Email this | Comments

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/u0ZSv7DCes8/

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Placenta on toast? Could we derive benefits from ingesting afterbirth?

ScienceDaily (Mar. 27, 2012) ? Almost all non-human mammals eat placenta for good reasons. Are we missing something? A paper by neuroscientists at the University at Buffalo and Buffalo State College suggests that ingestion of components of afterbirth or placenta -- placentophagia -- may offer benefits to human mothers and perhaps to non-mothers and males.

They say this possibility does not warrant the wholesale ingestion of afterbirth, for some very good reasons, but that it deserves further study.

Mark Kristal, PhD, professor of psychology and neuroscience at UB, directs the graduate program in behavioral neuroscience, and has studied placentophagia for more than 40 years. He is recognized as a principle expert in the field.

Kristal's article "Placentophagia in Human and Nonhuman Mammals: Causes and Consequences," will be published in the March 30 issue of the journal Ecology of Food and Nutrition, which will be devoted to the subject of placentophagia.

Kristal's co-authors are Jean M. DiPirro, PhD, associate professor, Department of Psychology, Buffalo State College, and Alexis C. Thompson, PhD, research associate professor, UB Department of Psychology and a research scientist in the UB Research Institute on Addictions.

They point out that the benefits of placenta ingestion (as well as the ingestion of amniotic fluid) by non-human mammalian mothers are significant. It provokes an increase in mother-infant interaction, for instance, and increases the effects of pregnancy-mediated analgesia in the delivering mother. It also potentiates opioid circuits in the maternal brain that facilitate the onset of caretaking behavior, and suppresses postpartum pseudopregnancy, thereby increasing the possibilities for fertilization.

"Human childbirth is fraught with additional problems for which there are no practical nonhuman animal models," says Kristal, citing postpartum depression, failure to bond and maternal hostility toward the infant.

He says ingested afterbirth may contain components that ameliorate these problems, but although there have been many anecdotal claims made for human placentophagia, the issue has not been tested empirically.

"If such studies are undertaken," he says, "the results, if positive, will be medically relevant. If the results are negative, speculations and recommendations will persist, as it is not possible to prove the negative."

Kristal says there is a current fad of ingesting encapsulated placenta, which mirrors unverified reports in the 1960s and 1970s of people in back-to-nature communes cooking and eating human placentas. The upsurge in recent anecdotal reports of the benefits of taking placenta by new mothers, irrespective of dose, method of preparation, or time course, suggests more of a placebo effect than a medicinal effect.

"People will do anything," Kristal says, "but we shouldn't read too much significance into reports of such exceptions, even if they are accurate, because they are neither reliable nor valid studies. My own studies found no evidence of the routine practice of placentophagia in other cultures, findings supported by a recent extensive study by anthropologists at the University of Nevada, Las Vegas.

"The more challenging anthropological question is," he says, "'Why don't humans engage in placentophagia as a biological imperative as so many other mammals apparently do?' because we clearly do not do this as a matter of course today and apparently never have. Perhaps for humans, there is a greater adaptive advantage to not eating the placenta." The paper discusses some possibilities in this regard.

"Whether or not we learn why humans do not do this, it is important for us to search for the medicinal or behavioral benefits of components of afterbirth for the same reasons that we search for plant-based medicinal substances," Kristal says.

"The outcome of such a quest need not be an exhortation for women to eat afterbirth, but for scientists to isolate and identify the molecule or molecules that produce the beneficial effect and use it to design pharmacological tools," he says.

He adds, "In the case of Placental Opioid-Enhancing Factor or POEF and enhanced opioid-mediated analgesia, for instance, we have determined through earlier studies that not only is the effect nonspecific in regard to species, but it is also nonspecific in regard to sex.

"That means that although males, who in all probability do not make the molecule, have the ability to respond to it," Kristal says.

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Story Source:

The above story is reprinted from materials provided by University at Buffalo, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. Mark Kristal et al. Placentophagia in Human and Nonhuman Mammals: Causes and Consequences. Ecology of Food and Nutrition, March 30, 2012

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2012/03/120327152826.htm

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All Regarding Baths and Showers | The Brigante Brand Home ...

Posted by admin on March 25, 2012 |
in Bath and Shower
as Baths, Regarding, Showers

We tend to pay therefore abundant cash on looking after our body. We tend to move to spas and sweetness parlors in our effort to look sensible and pay hours of our time and tons of bucks on trying fresh. However if you?re wanting at an inexpensive way to remain spruced up then nothing can beat a long and opulent bath. The importance of having a tub in maintaining a healthy body can?t be negated. It does not cost you abundant to own a bath. It?s most indulgent to require a thin dip in an exceedingly cast iron bath once a hard day at work. It enables you to relax and release the stress that has engineered up during the day.
Let us have a observe the different types of bathing choices in the form of bathtubs and showers.

Free standing baths will be positioned wherever you want it in the bathroom. It is also terribly straightforward to clean the tub.

You?ll easily overturn it to clean the underside. If you want to clean the ground around the tub, you?ll be able to simply shift the bathtub to try and do so. As long because the plumbing is finished the proper means, you can play with the d?cor of the bathroom with free standing baths. Roll high baths are another example. This tub has edges that curve at the high giving a distinctive spherical result to the edge of the tub. They?re obtainable in different varieties of styles. The material they?re created of conjointly varies relying on the manufacturer. They?ll be made from enameled metals or copper, porcelain, wood, plastic, acrylic or even glass.

Solid iron baths are a terribly in style alternative among all due to their distinctive appearance. They?re very durable. You will realize several cast iron baths that are tons of years recent and still as sturdy.

In fact, manufacturers give warranty that they can last for as long as they?re owned. The bathtubs are significant however resist scratches and dent the best. The bathtubs have totally different designs. They conjointly return in numerous colours, shapes, depths and sizes.

Walk-In showers are useful for those that find it difficult to get out and in of the bathtub. It additionally saves a lot on time. Not many have the posh of sitting in the bath and enjoying a protracted bath. They like a quickie, go below the shower, put on the soap and wash it off. A walk-in shower allows them to try and do just that. They also facilitate to avoid wasting on space.

Frameless showers haven?t any doors. They have a thick and clear tempered glass enclosure that helps to offer them an open look. They?re straightforward to clean. The glass can be frosted, colored, tinted, opaque etc.

Thermostatic showers can sense changes in temperature and modify the temperature and flow of water accordingly. Some cut out the flow of water when a failure in its flow is detected. Some can even stop the user from selecting terribly high temperatures.
With thus several options offered, you are positive to seek out something you prefer and take that soothing tub you have got continually been longing for.

Find More Bath And Shower Articles

Source: http://www.thebrigantebrand.com/2012/03/25/all-regarding-baths-and-showers/

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Afghan killing spree suspected to occur in two stages

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Source: http://news.yahoo.com/afghan-killing-spree-suspected-occur-two-stages-023739349.html

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The World's Most Powerful Non-Destructive Magnet Screams Like a Banshee [Video]

You don't normally associate any kind of sound with a magnet. But apparently that's because the ones stuck to your fridge aren't two million times as powerful as the Earth's magnetic field—like the one the Los Alamos Laboratory just created. More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/VwkB5Y9nFqI/the-worlds-most-powerful-non+destructive-magnet-screams-like-a-banshee

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Chargebacks, especially when selling online gaming branding ...

?Younger folks are practically born with credit cards nowadays,? said Duce Scarber, a payment solution market engineer with the Gunnells Eitniear Firm and Partnership, ?and are also practically built into the internet. It?s second nature to them, unlike those in older demographics who have more money to purchase online gaming branding items, but choose to do offline.? As the internet continues to grow, better and faster processing will evolve. Darci Aschbacher, author of the blockbuster book ?E-Business by 2014? believes that eventually there will be a form of ?i-cash? that freely flows between customers and merchants online. Stated Darci Aschbacher, ?Movement towards a personal cash card NOT credit card, is starting to begin. When that day arrives, payment processing for those looking to buy online gaming branding stuff will be extremely easy, reliable, and very fast.? ?We?ve slowly moved away from check processing to credit card sales,? said salesperson Evatt Barthelmes, who works on the staff of Valliant Fenwick and Penland Bormann LTD, ?mostly because check processing takes days, and credit cards are almost instant. Further, if the check bounces, and we?ve sold a online gaming branding product, it can take a month to track down the delinquent account holder and get our money back. With credit cards, its up to the respective bank to come up with the money.? Indeed, the days of sending checks in the mail may be over, especially as internet sales of online gaming branding related products continue to boom. Jankowski Scherb, Vice President of Customer Relations for mega-company Laplace Mcneese INC recently stated that payment solutions are needed more and more as customers flock to the internet to make purchases online. ?Essentially, we want fast processing, but also very secure processing. Customer confidence is extremely important in the online gaming branding industry, and we aim to be one of the top businesses in this market. In order to do that, business transactions must be clean,? added Asst VP Kimber Verhoff. The company also plans to bolster offline payment solutions as well. As the internet continues to build and advance, more and more retailers are demanding viable payment solutions for selling their online gaming branding wares online. Payment online is not as easy as it looks: security, credit checks, and balance inquiries have to be made in seconds, so that the merchant can be assured they will get their money, and the customer can be assured they will get their online gaming branding purchase. ?I?m excited to be starting up this new e-wallet,? said Myint Kreps, CEO of Myint Kreps LLC, ?because we?ve noted a huge demand for online gaming branding transactions online. In order to meet this demand, we?re going to need high end IT and fresh programming platforms. With these two elements teamed together, we believe we can provide payment solutions for online gaming branding companies and many others.? Further information regarding new payment processing methods for the online gaming branding industry can be found at www.Rollyson Scotty.com, an international authority on internet commerce. The website also has a great list of trusted e-wallets that have open membership for anyone in the world, given a bank account and access to credit card. ?I love shopping for online gaming branding stuff online,? stated Marvel Buchbinder University student Wittlin Shelhamer, ?because I have a student credit card that allows me to make internet purchases. Without it, I?d be paying double or triple for my books at the school bookstore, whereas online, I can find books second hand for a third of the price.? Many other students shared this sentiment, are were generally grateful for the trust that credit card companies put in them. Danesi Furfaro, assistant chairperson of the online gaming branding industry oversight committee, believes that top payment solution www.Paypal.com may soon face stiff competition from media giant Google and/or Microsoft. ?Look, as I see it,? stated Danesi Furfaro, ?we?ve got three players all vying for the same market: search, buy, and process. Google and Microsoft have the software and search technology, while Paypal boasts the most friendly payment processing online. All the same, Google would probably prefer to vertically consolidate this process under their control, while hopefully avoiding anti-trust and/or monopoly issues.?

Source: http://www.anzmac2008.org/?p=267

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Small business Advertising: Do-It-Yourself Advertising Compared to ...

Are you a modest to medium sized company proprietor For anyone who is, you might be searching for approaches to boost your customer base and your income in general. In case you are you, you may be interested in beginning a brand new marketing or marketing marketing campaign. In relation to business advertising and organization advertising, youll find that you possess a quantity of distinctive possibilities. Quite a few business enterprise proprietors choose to do their own immediate promoting promotions, while other people choose to utilize the services of an expert promotional advert agency.

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When utilizing the solutions of a professional promotional advert agency, numerous enterprise proprietors appreciate the time that theyre in a position to save. It really is no key that business advertising and marketing and business enterprise marketing are time-consuming duties, specially should you be unfamiliar with all the procedure. Must you choose to let an expert promotional advert company handle your business?s marketing and advertising and advertising, you will most likely come across yourself in a position to concentrate on other important tasks.

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Though there are numerous advantages to uses the solutions of an expert promotional advert agency, there also quite a few negatives to undertaking so as well. One of those disadvantages is the price. Selecting an expert promotional advertisement agency can be pretty expensive. Despite the price of performing so, many company proprietors come across it well well worth the fees. Actually, a lot of look at it from your standpoint of an organization investment; an investment that they will most likely see a return on.

If youre bored with utilizing an expert promotional advertisement company for your advantage, you might be considering understanding the positive aspects and disadvantages to doing your personal immediate marking promotions. As for the main drawback to undertaking your personal immediate advertising promotions, youll find that it could be time consuming to do. If you are fairly unfamiliar with enterprise advertising and marketing and company advertising, you might spend an excellent deal of ones time doing investigation then relying on trail and error. As formerly mentioned, numerous promotional advertisement companies already have confirmed marketing and advertising strategies in spot, which include reward or incentive applications.

Possibly, the largest advantage to performing your immediate advertising promotion, either your self or by getting one of the employees member get it done, would be the capital that you could have the ability to preserve oneself and your organization. This is excellent if you are running your small business on a budget. Although your time or perhaps the time of ones staff will price dollars, youll find that the price is usually reduced than that of utilizing a promotional advertisement company. Its also nice to get total control more than all marketing and marketing and advertising choices.

No matter if you choose to manage your own immediate advertising and marketing promotions or rely on professional help, you will need to take into account utilizing reward applications or consumer incentive applications for your benefit. These applications can incorporate advantages, like no cost merchandise or travel certificates, to new or returning shoppers. If you determine to perform your own direct advertising and marketing promotions, you will need to find an incentive organization to complete enterprise with. You will want one, such as the Infinity Incentive Team, that gives you the alternative of picking multiple promotional presents.

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Source: http://business-growth-strategies.info/small-business-advertising-do-it-yourself-advertising-compared-to-employing-a-promotional-advert-agency/

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Why Clearone for Video Conferencing? | drenalinband.com

There is a great competition in the world market today of the latest and most required equipments and facilities like Audio Conferencing system and its related products. Nevertheless, there is a company that is trusted in providing customers high definition audio, video, and web conferencing products and this company are Clearone. They are the industry?s first supplier and provider of wireless conferencing. Experience is their advantage. For many years, they have been supplying many organizations, offices, government agencies and homes with communication equipments. Their goal is making customers satisfied. The following are reasons why their clients are satisfied with their products.

? Consistent in producing high quality equipments. As the demand of most efficient way of communication rises, Clearone is consistently very resourceful to come up with fresh and competent communication products that meet the satisfaction of the customers. Their work force is composed of expert and skilled professionals. They aim to give their clients the most comprehensive solutions and create a natural communication environment in order for you to experience real presence set-up. High quality equipments are their output. They are the first source of conference phone that provides a wireless conferencing. They gain the reputation of being the leader, in the industry of communication, in high-end Audio Conferencing.

? Superior features. Clearone managed to give the clients wide range choices of products which have different levels of standard according to what you are looking for. Materials for audio, video and web applications passed different tests and procedures to insure that users will get the best result. The features of their equipments are superior to others. They are classy, innovative, and easy to access. Their products enhance presentation, collaboration, distance communications as well as multimedia applications. Video and Audio Conferencing, have never been this fast, clear, effective, and efficient, without the hands of the experts that continually looks for better services to offer the public.

? Reliable and dependable. Clearone is the company that is exceptionally reliable and dependable. They are in the service for more than two decades, and satisfaction of customers has always been their top priority. They have been supplying audio and video conferencing products to the world. Their customers include companies, big and small businesses, government agencies, educational institutions, community organizations, and churches. You can rely to them if you want only the best. This award winning company is committed to making you happy and contented as their products excel your expectations. When it comes to these equipments they are the name recognized. You can depend on them.

? Excellent service. Being recognized in the world market, as leader provider of audio and video conferencing technologies, Clearone has set a high standard of service. They are customer oriented and friendly. Their staff and team are composed of highly educated and trained professionals. They cater excellent servitude that is why their number of clients increases each day. As they dominate the professional conferencing space, their service is improved because it is their commitment to provide the highest quality hands-free audio, and video conferencing for any setting, from personal conferencing on cell phones, to office desktop conferencing, to large professional conferencing locations like training centers, auditoriums, classroom, courtrooms, boardrooms and coliseums.

Source: http://drenalinband.com/general/why-clearone-for-video-conferencing/

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Have The Samwers Gone Too Far With Their Blatant Amazon Clone Lazada?

Try as they might the poor innovative startups of Germany - we're talking guys like Soundcloud, Amen and 6wunderkinder to name just three - still have to deal with their industry's most famous exports being out-and-out cloners. Germany's most famous tech entrepreneurs are not Steve Jobs-like figures, original thinkers, but ruthless executors of other people's business plans, and even designs. The latest has appeared today in the form of Lazada, an Amazon.com rip-off so close to the original we do rather wonder whether this time the Samwer Brothers' photocopier in Berlin may have been used a little too liberally.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/1gwm5B1epk8/

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Effectively Use Business Marketing to Grow Your Online Business

[unable to retrieve full-text content]Just like a simple but highly important concern is having a firm understanding of your market. Understanding your market is perhaps one of the most important responsibilities you have toward your business. Knowing how to ...

Source: http://hellsing-ova.com/effectively-use-business-marketing-to-grow-your-online-business/1840/

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Looking for cheap essays online. I want to buy a ... - Obvious Articles

As we all know, essay writing is a common practice among students. In high schools and colleges, students always need to prepare quality assignments or essays. In some colleges, as a part of admission procedure, students are asked to write essays. So if you want to submit high-quality research papers, you can depend upon research paper writing services. These services allow you to buy a research paper from them. Some companies will produce cheap essays with the help of talented writers.

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Investing in active funds: what's the point? | Global Investing

Active vs passive investment is a long-lasting debate: active funds will tell you they deliver alpha (extra returns), but for a fee. Passive investment simply tracks the index so it?s cheaper. The?risk?is?you may underperform your?peers.

New research from Thomson Reuters Lipper throws up?an interesting twist in the debate: It found that?less than half of the?actively managed mutual funds in Europe outperformed their benchmarks?over the past 20 years.

The proportion of funds that outperformed varied from 26.7% in 2011, 40% over 3 years and 34.9% over the past 10 years.?While bond funds fare better over 3 years with 45.4% outperforming, the proportion tailed off dramatically over the 10-year period, falling to 16.2%.

For long-term investors, the fact that an active manager does not outperform in every calendar year is likely to be less significant than whether he/she can outperform over a longer?period. However, the result here is equally?unimpressive. The data showed that?the proportion of equity funds beating benchmarks in terms of rolling returns fell to 39.7% over a 10-year period (and just 17.4% for bonds). Your best bet seems to be in active equity funds investing in Asia Pacific ex-Japan (54.4% over 10 years).

Despite the findings, active funds are?a big industry: Assets of actively managed equity funds in Europe stand at just under 1.5 trillion euros, while index trackers have 160 billion euros and ETFs 139 billion euros. In other words, of the equity funds pot, passively managed products make up less than 17%.

Obviously, not everyone survives. Over the past 10 years in Europe,? 3,400 funds have been launched every year?on average?while 2,400 have been closed or merged. In other words, there has been a?net increase of 1,000 funds each year (across all asset classes and for both actively?and passively managed funds). ?But you are spoiled for choice: the current universe stands at around 35,000?funds.

Source: http://blogs.reuters.com/globalinvesting/2012/03/19/investing-in-active-funds-whats-the-point/

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Windows Phone Tango ROM leaks out, reveals support for more background tasks

Rumors point toward a probable Tango launch in China on the 21st of the month, but folks over at the XDA forums already have their eager palms on a "world first" ROM. The leaked Windows Phone goodies show support for more multitasking apps, getting a boost from the five that are currently supported in Mango to eight. Additionally, Tango (8773) seems to use less no-task memory than its older 8107 sibling, while it also brings Delivery Confirmation and Acknowledgment to its MMS settings. More secrets are bound to shell out over the next few hours, and you can keep yourself entertained by checking what else slipped through the cracks at the XDA site by clicking our source links below.

Windows Phone Tango ROM leaks out, reveals support for more background tasks originally appeared on Engadget on Tue, 20 Mar 2012 13:41:00 EDT. Please see our terms for use of feeds.

Permalink Phone Arena  |  XDA-Developers (1), (2)  | Email this | Comments

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/4_6m4My3FOc/

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US, EU, and Japan challenge China?s rare earth export restrictions

In a tripartite challenge against China's export restrictions on rare earth materials, the US, European Union, and Japan filed a complaint with the World Trade Organization.?

The United States, the European Union and Japan, lodged a joint complaint at the World Trade Organization (WTO) Tuesday regarding?China?s export restrictions on rare earth exports, materials critical for the production of numerous high-tech products.?

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The three trade powers aim to increase the pressure on Beijing?s export quotas of raw materials, asking the WTO for dispute settlement consultations, which is the first step in a longer process.

The US, EU, and Japan argue that by setting export restrictions such as quotas and taxes, China artificially lowers domestic prices and boosts domestic supply, thus granting local manufacturers an advantage against foreign competition. As a result, Chinese companies have access to more and cheaper rare earth materials, and foreign firms have to grapple with smaller and more expensive supplies.

"China's restrictions on rare earths and other products violate international trade rules and must be removed," said EU Trade Commissioner?Karel De Guchtin a?EU statement.

Rare earth minerals consist of a group of 17 elements with widespread applications in hi-tech businesses, cell phones, computers, light bulbs, and green products such as wind turbines and hybrid cars.?

China currently monopolizes the rare earths trade, holding approximately 30 percent of the global reserves and producing?97 percent share of the world supply,?according to?the ruling Chinese Communist party's official organ, the?People?s Daily. ?For instance,?China accounts for 91 percent of the world production of Tungsten, a chemical element used in the electronics, aerospace, medical, and automotive sectors. ?

Facing re-election later in the year, and with the US economy already dominating the campaign, the Obama administration seems to assume a more confrontational stance on Beijing?s trade policies amid Republican accusations of being too soft with China.

Source: http://rss.csmonitor.com/~r/csmonitor/globalnews/~3/va3TH40mYZw/US-EU-and-Japan-challenge-China-s-rare-earth-export-restrictions

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Supplies For Home Improvement | HOME IMPROVEMENT CAST

Supplies For Home Improvement

People have continually said that the sole issue constant within the world is modification. an equivalent issue additionally applies for the house when the person thinks that a trifle reworking ought to be done.

Home improvement are often drained as very little as a 0.5 every day or might last weeks particularly for a serious project. you ought to continually check that there are enough provides in the least times so as to avoid another trip to the ironmongery store on things that are lacking.

You can 1st do that by creating an assessment of the scale of the project. tiny comes are often planned simply. ought to this need rewiring the house or constructing an extra area, then the you ought to work with the contractor on the items required to form this work.

It is advisable for you to try to to the looking instead of letting the contractor do that. you?ll be able to keep track of the expenses and opt for materials that are each sturdy are reasonable.

Here Are a number of The Common Things required For Home Improvement;

You won?t ought to obtain an oversized range of nails and screws. they?re going to are available totally different sizes and used on various things and having a trifle quite enough are sufficient to end the duty.

Painting is another expense. the sole time that the proper color can look its best is to use 2 coatings on the wall. The person will calculate betting on the world where this can be done and build an estimate of what proportion is required. This calculation can work well notwithstanding the colour used.

Wood is employed in most homes. Wood are often used to form shelves or a wall. you?ll obtain variety of items in varied dimensions letting the employees do the project with the right tools.

Electrical work would require lots of wire. you?ll obtain this by the box or by the yard. you wish to form certain that you just get the proper kind that may be utilized by an electrician. this can stop short circuits from occurring within the home that the person needs to enhance.

These provides are out there in any ironmongery store shut your home. All you have got to try to to is build a listing then drive over to shop for this stuff. ought to there be quite one search in city, maybe it?d be an honest plan to canvass around so you avoid wasting cash on the expenses for the advance.

? Trackback URI This entry (permalink) was posted on Saturday, March 17, 2012, at 6:40 am by arazone. Filed in SELF HOME IMPROVEMENT and tagged electrical work, electrician, equivalent, home, home improvement, nails, person, right tools, screws, shelves, short circuits, sole issue, store, trifle, work.

Source: http://homeimprovementcast.net/self-home-improvement/supplies-for-home-improvement/

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Sales Process Management ? The Key to Unlocking the Potential of ...

According to legendary quality expert W. Edwards Deming, there is one critical, but often overlooked, factor upon which success in almost any business endeavor depends. The ability of your sales team to meet and exceed your revenue targets will be determined largely by your awareness, or lack of awareness, of this one thing. It amazes me how many companies neglect it entirely, focusing instead on individuals and performance issues while the real problem goes unnoticed and unaddressed. Obviously it is vital for you to understand this important component and learn how to manage it properly so that you can unlock the full potential of your sales organization.

According to Dr. Deming, the critical component is your system, or process. For the purposes of our discussion, we?ll be focusing on the process that has to do with generating sales?your selling process. In my experience it doesn?t matter how talented, educated, or experienced your salespeople are, or how hard they work at it, there remains a very large gap between the actual results they will produce and the results they could have produced had someone been paying attention to process. In today?s ultra competitive business environment, where the margin between winning and losing is so slight, I am surprised at how many companies continue to ignore an area that holds such potential for drastic increases in productivity and bottom line results.It?s easy to say that your salespeople could be producing better results. It?s not so easy to actually demonstrate it and then formulate a workable plan to do something about it. Most managers would agree there?s always room for improvement. The challenge lies in knowing where to look in order to find the weaknesses in the selling process that are holding your people back. It?s hard to stop the bleeding when you can?t find the cut?or worse yet?when you don?t even know there?s a cut. Most companies don?t even know where to start. In that sense, it?s easier to manage people than to engineer process improvement. It?s always easier to treat the symptom than to actually diagnose and treat the underlying cause. The result is a selling environment where the true reasons for most mistakes and failures go unaddressed and are blamed on people instead. Companies who operate this way often find themselves grappling with the same basic problems year after year with the only change being the people doing the grappling. It?s an ineffective and expensive proposition, certainly much more so than teaching your sales managers how to apply the principles of Sales Process Management.

Sales Process Management (SPM) promises to do more than just identify and improve the weaknesses in your selling process. Another major benefit you will enjoy when you make the commitment to SPM is seeing the best practices in your selling process identified and duplicated across your entire organization. I?ve heard many leaders talk about implementing best practices but have seen very few of them actually manage to consistently achieve it.

I first stumbled upon the benefits of SPM a few years ago when I was on the other side of the management fence selling online recruiting solutions for a major Internet company. The Internet bubble had burst and the economy was starting to slow down. As a result, our prospects and clients weren?t hiring at the same rapid pace as they had been before.

Sales started to slump. Salespeople who had always hit their numbers were now coming up short every month. Management focused immediately on inspecting and monitoring the individual performance of the salespeople. The decision came back that we were not making the necessary number of daily sales calls. A resolution was made to mandate ratcheting up the activity levels on the floor. If we failed to make X percent more dials every day we could be penalized or otherwise punished. Incentives were introduced to reinforce and reward the required behaviors.

Employee morale plummeted. Salespeople expressed concern that management was unfairly targeting them for blame. Management expressed concern that perhaps many salespeople had been taking advantage of the situation during the good times and didn?t really care about the company, or, worse yet, were lazy and needed to be weeded out. The mandate had its intended effect? at least on call volume. The average number of daily sales calls on the floor did increase dramatically. Unfortunately this increase in the number of sales calls did not result in a corresponding increase in sales and revenue.

During this time, my focus was on finding something that would work to produce measurable results for me. Initially I ratcheted up my activity levels too. In order to accomplish this I began coming in early and staying late. After a few months of this I noticed that although I was working harder and longer, and sacrificing time with my family to do it, I wasn?t seeing any appreciable return on my investment of additional time and energy. I began to realize that I wasn?t addressing the real problem. The market had changed dramatically while my sales process had remained the same. I was doing the exact same things I had been doing when the market was hot. The only difference was that I was now doing a lot more of them.

I began to analyze how the marketplace was different now and to think about changes I could make to my own approach and what the results were likely to be. Unwittingly I was applying SPM to my own selling process!

I recognized that during the time the economy had been booming almost every company seemed to be hiring. A salesperson could just pick up the phone and dial a prospect (seemingly at random), and chances were that they would be hiring or could refer you to someone who was. I had always kept data on the number of sales calls I was making and the results and success ratios my efforts generated. The data showed that before the bubble had burst, nearly one in three of my sales calls resulted in a lead. It was the perfect market for making as many sales calls as you could possibly fit into the day.

The present situation was very different. I was now making almost 30 dials, on average, to get to that same lead. I did the math and found that increasing my outbound sales calls by the suggested 50 percent wasn?t going to get me even close to where I needed to be. I would have needed almost a 1000 percent increase in call volume to come close!

Another difference was that, whereas during the boom, I could approach a prospect without specific knowledge of their business or hiring plans and effectively communicate using very general terms, now, leads were so few and far between that I needed to have a more thorough knowledge, and a specific, customized solution prepared in order to engage the prospect in any kind of meaningful discussion. Each lead was too rare and too valuable to risk losing on a random, generalized cold call.

I concluded that I needed to change my selling process from one in which I was making a higher volume of random sales calls, to one where I was making a lower volume of more targeted inquiries. Talk about flipping conventional wisdom on its head! I couldn?t argue with the numbers, however, and, after some initial hand wringing, my manager couldn?t either. He agreed to let me try out my new process.

The new approach began to yield results immediately. I was opening up far more new cases than ever before and my sales numbers jumped up higher than they had been when the economy was booming! I began to apply the same thinking to every process I was using.

First, I would identify all of the activities within my current selling process. Then I would analyze each one to try to understand its true importance to advancing the sale and producing the intended outcome. Whenever possible I would look for patterns and ways to measure the cumulative results of each activity or behavior. I soon found that by taking the time to isolate and understand the role each activity played within the context of my whole selling process, I could better reason from cause to effect and more accurately pin point the relative strengths and weaknesses of each. The result was a sort of behavior pattern algorithm that told an accurate story of my process from beginning to end.

After gaining an understanding of exactly what I was doing and how each component of my process contributed to the outcome I wanted to achieve, I would look for ways to improve upon my results. I would repeat this process over and over again; continuously looking to identify inefficiencies and replace them with new, improved ways of doing things better. Often the improvements would come as a result of talking with and observing other top performing salespeople. Now that I knew what I was looking for, I could more readily identify what others were doing differently in the same area that was allowing them to perform at a higher level and immediately incorporate it into my own process.

The results were immediate and dramatic, enabling me to finish 2002 as the top telesales rep in the entire company. Since then, I?ve successfully introduced SPM to my clients and to my own salespeople and have never seen it fail to produce the same outstanding results. SPM is easy to implement and works in any situation, economy, environment, industry, or company. It will work for you too.

Source: http://www.alaskasmallbusinessmarketing.com/sales-management/sales-process-management-the-key-to-unlocking-the-potential-of-your-sales-force.html

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